Clean Critically

Contamination happens long before the product enters the cleanroom; critical cleaning often happens long before the product enters the cleanroom.

Effective Garment Program

An effective cleanroom garment program is a vital component of any successful cleanroom operation, but it can often seem like a necessary evil; an expense item that seems to be forever trending upwards over budget.

Cutting Costs In Cleanroom Apparel

Diligently re-bidding cleanroom laundry service isn’t the only thing that you can do to manage cleanroom garment costs. The gownroom is the venue where the cleanroom garment program must perform.

Critically Clean

Too often, cleaning the cleanroom to a particular standard becomes an end in itself; reaching the goal or staying within limits of contamination may not be adequate. We have to meet or exceed the requirements.

Cleanroom Cleaning Education

Teaching employees to adhere to rules of behavior or to a specific cleaning protocol is necessary. However, for both product and cleanrooms, there is no substitute for understanding the “why” of the cleaning process.

The Power is Out, Now What?

Power failure, by definition, is a total loss of utility power. Utility power losses are caused by numerous events including lightning strikes, downed power lines, transformer malfunctions, over demands on the grid, accidents, weather anomalies, and natural disasters.

Air Showers and Cleanroom Operation

Air showers are just one factor in ensuring good cleanroom performance. Proper worker training, documented procedures, and a well-maintained system will increase production yields and reduce product defects and costs.

Light Does Not Displace Heavy

If all soil and cleaning agent components are soluble, rinsing is dilution. If some components are insoluble, rinsing is also displacement. A client found two minor soil components were heavy oils, insoluble in water. Displacement/rinsing of heavy insolubles with light solubles is equivalent to pushing a chain uphill. About Your Site How similar is your rinsing system to my client’s? Would an inspection yield any of the same surprises? Rinsing and cleaning equipment perform no better than the details which make up their design.

Flammability Hazards of Aerosol-Dispensed Cleaning Agents

Many believe that aerosols are safe below their flash points. Serious fires have occurred in the chemical process industries because of that belief. In fact, aerosols of combustible liquids at temperatures well below their flash points can be ignited as can vapor.

Design for Growth?

Overdesign is one of the primary drivers of cleanroom size—and cost. While it is important to plan for production capacity growth, there is a big downside.

Advantages of Modular Cleanrooms

Modular, free-standing cleanrooms have many distinct advantages over their fixed wall counterparts. Using modular rooms greatly reduces design, engineering, and construction time, thereby reducing costs.

The Cost of USP 797 Compliance

The costs related to USP 797 compliance can vary greatly. Your specific needs will depend on your current compounding environment, as well as the types of CSPs being prepared. A key consideration, however, is the cost of non-compliance in the event that a contamination is tracked to your facility.