Cleanroom Design
ISO 8573 Certification of Air Compressors for Contaminants and Air Purity Classification
By Rudy Pina
To certify a compressed air system for purity classification in accordance with the ISO document 8573 can result in opening the proverbial “Pandora’s Box.”
Dynamic Variation of Air Change Rates
By Gordon P. Sharp
There continues to be great debate over the correct value for the minimum air change rates (ACH) for laboratories. But there is a new approach to saving energy and enhancing safety.
The Bottom Line on Buying a Cleanroom System
By Rick Dobson
What questions, as a potential buyer, do you need to ask to ensure your performance specification will be met?
Nanotechnology Cleanroom - Design on A Dime
By Raymond K. Scheider
The tight budget of today’s nanotechnology facility start-ups makes the need for small scale cleanroom solutions as important as ever.
The Incompatibilities of Semiconductor and Life Science Cleanrooms
By Deric Haddad
There are distinct differences in the basic design criteria between semiconductor and biopharma cleanrooms — starting with the floors, ceilings, and walls.
Facility Design As A Training Platform
By Bikash Chatterjee
It is safe to say the pharmaceutical and biotech market today bears little resemblance to the market of the last twenty years.
Point of View: The Value of 3rd Party Certification
By Ralph Kraft
Once you have your cleanroom constructed, the HVAC system balanced, and the room(s) precision cleaned, your cleanroom is now ready to be certified to the classification of cleanliness it was designed to.
At this point, you have two choices: 1) you can do it in-house, or 2) hire an experienced Certification Agency.
Cleanroom Facility Construction Options
By Paul Nesdore
Does construction method matter?
Design Concepts in Air Management Systems
By Nejat Babür, P.E.
A comparison between biotech facilities and semiconductor facilities in HVAC system applications and components
Diffuser Models For Airflow Simulation
By Jelena Srebric, Ph.D., Andrew Manning, Qingyan Chen, Ph.D.
Accurate simulation of the airflow and heat transfer in cleanrooms is highly dependent on the diffuser, yet diffusers have traditionally been very difficult to model.
Catching The Drift
By Kevin Bull
Knowing what to look for in product specifications can initiate incisive questioning of manufacturers about the effectiveness of their humidity measuring systems.
Case Study: Airflow Simulation Ensures +/-1 F Temperature Range
By Christopher Wark
A pharmaceutical manufacturer needed to keep space temperatures in a warehouse between 68 °F and 78 °F to maximize the shelf lives of their products.
Case Study: Georgia Tech's New Marcus Nantechnology Building Cleanroom Facilities
By Ed Brace
The Georgia Institute of Technology (Atlanta, GA) is poised to advance its research standing with an $80 million nanotechnology center that will bring together the physical and biological sciences in a unique fusion of disciplines.
Reducing Cost and Complexity of Managed Cleanrooms
By Howard Abramowitz
This article will extend the focus beyond the FFU to the interfacing system. The opportunities and options in the interface can be as simple as manual controls to sophisticated stand-alone systems or even interfaces that will tie into building management central control rooms. With smart FFU products being more readily available, the utilization of these units in “smart systems” is the logical progression.
Case Study: Stabilizing Cleanroom Humidity and Temperature
By Bob Reichenbach
The air-handling compressors were constantly slamming on and off, but the main problem was that I could never get the humidity low enough to stay within our specs, which are more stringent than the federal cleanroom standards.
The Green Clean Laboratory
By Raymond K. Scheider
The notion of sustainable construction as “those materials and methods used to upgrade, construct, and maintain a structure that meets the needs of the present without compromising the ability of future generations to meet their own needs” has been percolating through society for some time now.
Smart FFUs Change The Landscape For Cleanroom Control Options
By Howard Abramowitz
The use of fan filter units (FFUs) continues to gain market share over centralized systems as their performance is improved while installed costs are driven lower, eliminating the key obstacle of a higher installed cost.
Chemical Filtration Strategies For The Control of Airborne Molecular Contamination, Part 2
By Christopher Muller, Brad Stanley
It is well known that a single chemical filter medium may not adequately control multiple contaminants or all classes of AMC. The types and numbers of AMC that one would encounter make it likely that air-cleaning systems need to be equipped with multiple stages of specialized chemical filter media.
Building A Clean Research Laboratory
By Steve Yellin, Don Acker
When approaching the project of building a research lab, there are many questions that need to be answered.
Case Study: Purdue Nanotechnology Labs
By William Oh
Purdue Nanotechnology Labs employ advanced grounding Device to ensure a constant flow of clean air.
Airflow Modeling Simulation Optimizes Cleanroom Design
By Andrew Manning
A case study illustrating the use of airflow modeling software in the design of a pharmaceutical cleanroom.
New Closed-Loop Controls For Minienvironments
By Howard Abramowitz
Often, to ease cost constraints, there is a growing placement of higher purity cleanroom minienvironments inside a larger ballroom space.
Case Study: Utilizing Lower-Cost FFU Systems
By Craig Vernick, Howard Abramowitz, Jim Akers, PH.D., Jim Schwartz
A combination of smart design, innovation, and new product availability are giving companies the option of upgrading to “smarter” systems without having to pay the upscale price.
HVAC Systems in Compound Semiconductor Fabs
By John McKenna, P.E.
The stages of operational transition will have a direct impact on the HVAC systems required to support the different manufacturing environments.
Cleanroom FFU Controllers
By Howard Abramowitz
Fan filter unit (FFU) implementation continues to be the preferred solution for new cleanroom installations both large and small. Communication and control of these FFU systems have been confined solely to the large system installations, leaving the small rooms to continue using manual set-and-forget FFUs.