Selecting an appropriate adiabatic humidifier can result in energy efficiency, worker comfort, and increased productivity. Air conditioning, heating, and fresh air intake during winter conditions and dry summer months cause electrostatic discharge in cleanroom environments.
The future processes and facilities will be driven by the product, and by economic and regional parameters, but the key will be flexibility. With an increasing diversity of therapies and drug product ranges, facility designs also require diversification.
As the geometries of circuitry shrink, the drying of the substrate becomes a more critical step. In the production of microelectronics, substrate drying to obtain a clean, contamination-free surface often centers on the term “Marangoni drying.”
By creating a small electrical field that removes salts from seawater, university chemists have introduced a new method for the desalination of seawater that consumes less energy and is dramatically simpler than conventional techniques.
Letter From the Editor - July/August 2013
Manufacturers often ask how to achieve a clean space without using a cleanroom. There are many reasons to do this, including achieving a reasonable process flow and assuring economic competitiveness. Evaluate gloves and other protective equipment. Particularly at non-cleanroom stages of production, the Industrial Hygienist may be in charge of specification.
To test a clean zone, there are several issues like smoke reflux, dead spots, and numerous smoke deviations to look for. It is important not to separate the media filter from the wall since the farther it is from the wall, the more reflux can be found.
Alternative technologies are available for the rapid detection of microorganisms.
To ensure efficient and reproducible cleaning, it is essential to match the cleaning agent to the plant technology. That is why so many different cleaning systems are available.
The ever-increasing demand for reliability, continuing miniaturization, and the growing number of faults in electronic components manufactured in no-clean processes all combine to put the focus back on cleaning in electronics manufacturing. The industry offers a variety of solutions to finding the optimal cleaning process.
Compendial microbiological methods have been in existence for many years, with only minor changes being incorporated. Recently, more rapid technologies have emerged and, in some cases, have received regulatory approval as alternatives to the traditional compendial tests.
When cleanrooms are used in manufacturing or scientific research, the doors and framing materials must have proper gaskets and seals to not allow contaminated air in or out of the area, and the door hardware must close and reseal after each personnel passage. However, additional door devices—such as card access systems, electric locks, station controls, and traffic lights—may be necessary to limit access to authorized persons.
As a Registered Cleanroom Certification Professional, I have seen an increase in the use of "clean zones" inside of cleanrooms in pharmacies. There are numerous types of unidirectional-flow devices that have been used in the past; however, when using a unidirectional-flow device in the compounding processes, the suppliers, customers, and certifiers need to keep in mind the meaning of the direct compounding area, first air, and critical site.
The HVAC system in any controlled environment is the kingpin of clean. When it comes to cleanroom HVAC, it's all about contaminants and environment control.